Trina Basu

I received a B.S in Neuroscience from the University of Illinois at Chicago. Here, I worked as an undergraduate research assistant in Dr. Michael Ragozzino’s lab where I helped generate data in understanding the differential role of 5-HT2A and 5-HT2C receptors in behavioral inflexibility and working memory. I pursued my Ph.D in Neuroscience at the University of Wisconsin-Madison in Dr. Avtar Roopra’s laboratory. My thesis focused on unraveling the role for class I histone deacetylases (HDACs) in contributing to the synaptic plasticity deficits and a novel seizure phenotype in a mouse model of Tuberous Sclerosis Complex (TSC). As a postdoc in Dr. Jamie Maguire’s lab, I will build upon my background in epilepsy by utilizing new techniques to explore how status epilepticus induced hyperactivation of the hypothalamic-pituitary-adrenal (HPA) axis can exacerbate pathology associated with chronic epilepsy, alter neural network communication and contribute to the co-morbid appearance of anxiety and depression in epilepsy.